PDC 404

Skin Exposure and Biological Monitoring of Chemicals



introductory | Credits: 8 CM Credit Hours / 0.8 CEU / 0.5 CMP
Sunday, May 22 | 8:00 AM – 5:00 PM
Limit: 35


Big Data: Data Management & Interpretation, Biological Monitoring, Exposure Assessment Strategies, Protective Clothing and Equipment


This course covers the fundamentals of how skin exposure and biological monitoring of chemicals are related to occupational exposures and what industrial hygienists need to do to recognize, evaluate, control, and prevent health hazards when skin exposure predominates over inhalation exposure. Biological monitoring, skin measurement techniques, interpretation of surface skin measurement data, models for skin absorption, computer models for oral, skin and inhalation absorption, guidelines, regulations, and control measures will be discussed. A case study on toluene diisocyanate will present examples of both inhalation and skin routes of exposure. How to develop and implement a biomonitoring and skin exposure measurement program as part of a facility Health and Safety Plan will be presented. Breakout sessions will use an in-depth case study to develop an initial approach to both inhalation and skin exposure from four different materials: lead; benzene; polyaromatic hydrocarbons (PAHs) or polynuclear aromatics (PNAs); and mercury. The groups will then meet together to present their findings, followed by a question-and-answer period on biological monitoring-skin exposure problems.


High school chemistry (organic and inorganic and knowledge of chemical bonding) and calculus are needed. Experience in the field will be helpful.

Learning Aids

Participants must bring a scientific calculator, laptop, OR tablet/iPad.

Value Added

Interact with work personnel, peers, and health professionals on the necessity for biological monitoring/skin exposure measurements. Use the course guidance materials for real world cases and for the course taker’s workplace.


Upon completion, participants will be able to:

  • Know and understand the terms used in biological monitoring and skin exposure field sampling.
  • Assess the necessity of biological monitoring and skin exposure in a workplace.
  • Identify the advantages and limitations of biological monitoring and skin exposure measurements.
  • Select the appropriate biological monitoring markers and their measurement techniques.
  • Develop, implement, and conduct a biological monitoring skin exposure program in a workplace.
  • Interpret and communicate biological monitoring and skin exposure results.
  • Write a biological monitoring and skin exposure plan.


  • Introductions
  • What are biological monitoring, regulations, and guidelines, and how can they be used?
  • The skin, dermal exposure and an overview of how biological monitoring data can be used to estimate skin exposure
  • Toluene Diisocyanate (TDI) exercise
  • How to develop and implement a biomonitoring and skin exposure measurement program
  • Lecture on compounds to be discussed in breakout sessions
  • Breakout sessions
  • Course conclusions and evaluation

Transfer of Knowledge

Instructors will evaluate participants understanding of the materials presented based on:

  • Post PDC test
  • Hands-on demonstrations and practicum
  • Practice exercises
  • Workshops
  • Group activities
  • Interactive games

Course Survey Link: https://www.surveymonkey.com/r/16PDC404

Sponsoring Committee

Biological Monitoring